The 3 Daily Supplements Everyone Should Be Taking For Longevity | Mark Hyman



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Our food supply is dramatically less nutrient rich than it has ever been, and it’s taking a toll on our health. A shocking 99 percent of Americans are nutrient deficient, including over 90 percent who are deficient in omega 3 fats and 50 percent who are deficient in magnesium.

In this episode of my Masterclass series, I am interviewed by my good friend and podcast host, Dhru Purohit, about the top supplements for longevity, especially NAD, which inhibits inflammation, increases metabolism, and increases insulin sensitivity. We also discuss how to critically evaluate supplement research and much more.

Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset.

This episode is brought to you by Rupa Health, Paleovalley, and ButcherBox.

Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at

Paleovalley is offering my listeners 15% off their entire first order. Just go to to check out all their clean Paleo products and take advantage of this deal.

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32 comments

  1. THANK YOU.PISTACHIO IS RICH IN MELATONIN ,BUT CHECK NOT ROASTED ,UNSALTED.TO REDUCE CHOLESTEROL ,DID EXPERIMENT ON MYSELF,THREE WWEEKS NO ANIMALE PRODUCTS AND NO DROP OF OIL,TOTAL CHOLESTEROL DROPPED FROM 7.4 MMOL/LTO 4.8 MMOL/L,BUT MY LIVER FUNCTION TESTS WRE BECOMING HIGHER BUT STILL WITHIN NORMAL RANGE,SO I TOOK ONE TABLESPOON COLD PRESSED ORGANIC EXTRA VIRIN OLIVE OIL.THAT HIGH LEVEL OF CHOLESTEROL WAS DURIN DRY FASTING IN RAMADAN IN HOT ARABIC COUNTRY .IT COULD BE SEVER DEHYDRATION.BUT THE PRINCIPLE IS CUT ALL ANIMAL PRODUCTS.

  2. We are Saved by Grace Through FAITH NOT WORKS. Salvation is a free gift from GOD given to those all who will believe LORD JESUS CHRIST DIED AS A SALVATION LAMB for our sins by the BLOOD OF LORD JESUS CHRIST HIS BLOOD CLEANSES Our SINS !!!

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  4. I drink a green juice everyday w spinach, blueberries, real organic cranberry juice ( not sugar filled cocktail), probiotic plain yogurt, and honey. My skin glows and I don’t get sick even pre pandemic.

  5. I am not a scientist clearly. But I have always been confused about the efficacy of mice studies with their body weight and systems being so minuscule compared to humans. Yet the dosage of testing is astronomically disproportionate to their size. I would love for a scientist to explain how that correlates to the human body and systems. It's not even close enough to be apples and oranges in my opinion it's more like a pebble and a boulder.

  6. Well, what is the point of carrying out studies if you not going to do it properly and correctly?

  7. I take the supplement described by Dr. Oz as "The number one supplement you've never heard of that you should be taking," and described by Dr. Mercola as his number 2 supplement of all supplements: Astaxanthin. (Number 1 is Vitamin D).

  8. For tests that traditional doctors dont want to do because they dont know how to interpret them, I hoped Dr. Hyman would say, "Take the test and I'LL interpret the results for you. Send them to me as an attachment to an email or fax to me at this number." That would have been cool.

  9. What's the relation to Toniiq products – that's who introduced us to Dr. Hyman – does Dr. Hyman promote Toniiq supplements? Or has a financial interest?

  10. I would LOVE to go to a functional medicine doctor, but it so difficult to find one where I live – I think the nearest one is nearly 2 hours away, and then there's the possibility of no space for a new patient.

  11. Complicated answer to a relatively simple question. So did. He ever answer the actual question? BTW statins cause ALS if you take them for many years.

  12. I stopped aging since I eat real food. I do not use powders or pills. I am getting pretty old, yet do not feel it.

  13. Pure niacin, as in nicotinic acid is dirt cheap and is just as good for NAD. JUST HAVE TO PUT UP WITH THE FLUSH.

  14. Lychees my favorite ever fruit!so sweet yet I feel like it regulates my blood sugar.
    Any data on that?

  15. Sorry but Dr Hyman does not look healthy to me! He has not managed to reverse aging it seems!! Whole food plant based diet is the only way! Dr Hyman breeds and sell cattle so obviously making lots of money out of grass fed beef! who in the world can afford grass fed beef and there is not enough land and pastures to feed the world this way! Deforestation, exploitation and torture are not a way to achieve health and world harmony Dr Hyman!!!

  16. Why don't u get with Dr. Gundry and make that pill with all the stuff in it that u described?

  17. As a community let’s stop the toxic radiation and effects on our brain and body from 4 and 5 g cell tower implementation. Especially since satellites and rogue mobile cell towers are in use i everywhere . Use of cell phone w 4 and 5 g increases radiation exposure . Towers would need to everywhere to work. Not only toxic also unsightly. Supplementation won’t stop environmental toxic exposure, we have to block the implementation of 4 and 5 g towers asap. Thank You.

  18. I love Mark Hyman but he has aged a lot since I last saw him. It seems fasting is the way to go to slow it a little but bottom line is we get old no matter what.

  19. I just found Resveracell. Also contains Quercetin phyrosome. This I think, is a way for someone to come in entry level because when you buy everything separately it is quite expensive. Just the NR Truniagen itsekf It’s about $60 and raspberry trawl alone about 40 you’re looking at 100 bucks and you’re not getting everything.

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